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  • Writer's pictureLiven Qian

MoS2 quantum dots featured fluorescent biosensor for multiple detection of cancer

文献作者:Yuhong Liu, Jinzha Zhang, Yang Shen, Jinduo Yan, Zaiying Hou, Chun Mao and Wenbo Zhao  《RSC Adv.》

ABSTRACTS

Transition metal ions, such as those generated through MoS2 material, possess an intrinsic fluorescence quenching property towards organic dye molecules; thus, they can be used to construct biosensors as quenchers. MoS2 QDs exhibit a high fluorescence quenching ability towards fluorescent dyes, possess large specific surface area and a large number of active sites to adsorb and quench more fluorescent probes, promoting sensitivity between quenching and the recovery signal. In addition, the lighter color of unstack-MoS2 QDs is beneficial to define the location of cancer cells compared to MoS2nanosheets. The novel MoS2 QDs-based biosensor demonstrates high sensitivity to MUC1 with a detection limit of 0.5 nM, and may become an important tool toward the detection of cancer cells.

SCREENSHOT

RELATED PRODUCTS

MUC1 (N → C: PDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSA) was obtained from China Peptides Co. Ltd. (Shanghai, China).

CHAINING

http://pubs.rsc.org/-/content/articlehtml/2017/ra/c7ra09300d



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