top of page

MOG35-55|MEVGWYRSPFSRVVHLYRNGK

  • Writer: Liven Qian
    Liven Qian
  • Oct 25, 2018
  • 1 min read

Tolerogenic Dendritic Cells Induced by BD750 Ameliorate Proinflammatory T cell Responses and Experimental Autoimmune Encephalitis in Mice

文献作者:Yan Zhou, Xiao Leng, Hua Li, Shuxia Yang, Tai Yang, Limei Li, Ying Xiong, Qiang Zou, Yang Liu, and Yantang Wang  《Molecular Medicine》

ABSTRACTS

BD750, a novel JAK3/STAT5 inhibitor, can inhibit T cell proliferation. This study aims to evaluate whether BD750 can induce tolerogenic dendritic cells (tolDC) and their function in experimental autoimmune encephalitis (EAE) in mice. Following BD750 treatment, lipopolysaccharide (LPS)-induced maturation of DCs, allogeneic T cell proliferation, Th1 and Th17 cell functional differentiation, and STAT5 and AKT activation were determined.

SCREENSHOT

RELATED PRODUCTS

myelin oligodendrocyte glycoprotein (MOG) 35-55 peptide

CHAINING

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630474/



Comments


Post: Blog2_Post

+86-(0)512-63930660-816

+86-(0)512-63009934

HQ:Suite 811, Building 8, No. 5600 Chuansha Road, Pudong New Area, Shanghai, China 201202
Branch: F4, 8 Pangyang Road, Wujiang, Suzhou, Jiangsu, China, 215200

  • Facebook
  • LinkedIn

©2018 by ChinaPeptides-Liven.

bottom of page