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Hepcidin protects grass carp (Ctenopharyngodon idellus) against Flavobacterium columnare infection v

  • Writer: Liven Qian
    Liven Qian
  • Nov 22, 2018
  • 1 min read

Hepcidin protects grass carp (Ctenopharyngodon idellus) against Flavobacterium columnare infection via regulating iron distribution and immune gene expression

Author:Xiaolei Wei, V.Sarath Babu, Li Lin, Yazhen Hu, Yulei Zhang, Xiaoling Liu, Jianguo Su, Jun Li, Lijuan Zhao, Gailing Yuan  《Fish & Shellfish Immunology》

ABSTRACTS

Columnaris disease (CD) caused by Flavobacterium columnare (F. columnare) is lack of knowledge on effective treatment measures. Bacterial pathogens require iron as an essential nutrient to infect the host. While hepcidin acts as a master regulator in iron metabolism, its contribution to host defense is emerging as complex and multifaceted. 

KEY WORDS

Hepcidin; Protective effect; Flavobacterium columnare; Ctenopharyngodon idellus; 

SCREENSHOT


RELATED PRODUCTS

CiHep mature peptide (QSHLSLCRYCCNCCRNKGCGYCCKF) was synthesized by a peptide synthesizer from ChinaPeptides (Shanghai, China) and analyzed by HPLC that the purity was >96.84

CHAINING

https://www.sciencedirect.com/science/article/pii/S1050464818300858



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